Once Daily Sustained-Release Matrix Tablet of Naproxen: Formulation and <i>In Vitro</i> Evaluation
نویسندگان
چکیده
منابع مشابه
Once Daily Sustained-Release Matrix Tablet of Naproxen: Formulation and In Vitro Evaluation
The objective of the present study was to develop once-daily sustained-release matrix tablets of naproxen, one of the most potent non-steroidal anti-inflammatory agents used in the treatment of arthritic pain. The tablets were prepared by direct compression method using hydrophilic matrix materials like Methocel K4M CR and Methocel K15M CR. The tablets were subjected to measurement of thickness...
متن کاملDesign and Formulation of Once Daily Naproxen Sustained Release Tablet Matrix from Methocel K 15M CR and Methocel K 100M CR
The purpose of this work was to develop once daily sustained release (SR) matrix tablets of naproxen, an anti-inflammatory agent. The tablets were prepared by wet granulation method along with hydrophilic matrix materials like Methocel K 15M CR and Methocel K 100M CR. The granules were evaluated for bulk density, angle of repose, compressibility index, total porosity and drug content. The ...
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The purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. Two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose K 100 (HPMCK) and Eudragit L 100. The granules were prepared by wet granulation method and thereby formulated as F-1, F-2. F...
متن کاملFormulation and evaluation of theophylline sustained release matrix tablet
In the present study sustained release matrix tablets of Theophylline were prepared by direct compression method using different grades and ratios of hydroxy propyl methyl cellulose in presence of ethyl cellulose to examine their influence on tablet properties and drug release profile. Theophylline is used to treat chronic obstructive pulmonary disease (COPD) and asthma. The drug has a narrow t...
متن کاملdesign and formulation of once daily naproxen sustained release tablet matrix from methocel k 15m cr and methocel k 100m cr
the purpose of this work was to develop once daily sustained release (sr) matrix tablets of naproxen, an anti-inflammatory agent. the tablets were prepared by wet granulation method along with hydrophilic matrix materials like methocel k 15m cr and methocel k 100m cr. the granules were evaluated for bulk density, angle of repose, compressibility index, total porosity and drug content. the table...
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ژورنال
عنوان ژورنال: Dhaka University Journal of Pharmaceutical Sciences
سال: 1970
ISSN: 1816-1839,1816-1820
DOI: 10.3329/dujps.v9i1.7429